Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000084.xml
Synthesis 1996; 1996(11): 1371-1374
DOI: 10.1055/s-1996-4376
DOI: 10.1055/s-1996-4376
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
Synthesis of a Boronic Acid Analogue of L-Ornithine
Further Information
Publication History
Publication Date:
31 December 2000 (online)
The asymmetric synthesis of (R)-1,4-diaminobutane-1-boronic acid dihydrochloride, the amino boronic acid analogue of L-ornithine, is described. The key step of our approach utilized the Matteson boronic ester homologation of (+)-pinanediol 3-azidopropaneboronate to create and control the stereochemistry of the chiral center.
polyamines - ornithine decarboxylase - asymmetric synthesis - α-amino boronic acid - homologation reaction