Synlett 1995; 1995(SI): 543-544
DOI: 10.1055/s-1995-5294
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A Concise Method for Stereocontrolled Preparation of Medium-Sized Lactones

Tao Wang, Jie Chen, Donald W. Landrey1 , Kang Zhao2
  • 1Department of Medicine, Columbia University, New York, NY 10032
  • 2Department of Chemistry, New York University, New York, NY10003
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Tributyltinlithium-initiated sequential alkylation of cycloalkenones with 1,4-dibromo-2-butene, followed by lead tetraacetate oxidative fragmentation, leads to stereoselective formation of medium sized allylic lactones.