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Synlett 1995; 1995(SI): 539-540
DOI: 10.1055/s-1995-5280
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Peptidic Ring Expansion. Synthesis of Ring-Expanded Macrocyclic Lactams by Amino Acid Insertion

Allen Borchardt, W. Clark Still*
  • *Department of Chemistry, Columbia University New York, New York 10027, USA
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Publication History

Publication Date:
31 December 2000 (online)

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Smiles rearrangements can be used to prepare macrocyclic peptides by introduction of amino acids into existing rings.

Ring expansion - macrocyclic peptides