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Synlett 1995; 1995(SI): 527-528
DOI: 10.1055/s-1995-5275
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Preparation of 3,6-Dihydro-2H-1,3-oxazines and Their Use as Potential 1,3-Amino Alcohol Synthons

John P. Cherkauskas, Robert M. Borzilleri, Joseph Sisko, Steven M. Weinreb*
  • *Department of Chemistry, The Pennsylvania State University, University Park, PA, 16802, USA
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Publication History

Publication Date:
31 December 2000 (online)

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3,6-Dihydro-2H-1,3-oxazines, which can be readily prepared by reaction of β-hydroxyaldehydes with N-sulfinyl-p-toluenesulfonamide, are useful intermediates for stereoselective synthesis of 1,3-amino alcohol derivatives.

N-sulfinyl-p-toluenesulfonamide - β-hydroxyaldehydes - tetrahydro-1,3-oxazines

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