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Synlett 1995; 1995(10): 1079-1080
DOI: 10.1055/s-1995-5175
DOI: 10.1055/s-1995-5175
letter
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An Efficient, Safe and Convenient One-Step Synthesis of β-Phenethylamines via Reductive Amination Reactions Utilizing Ti(OiPr)4 and NaBH4
Further Information
Publication History
Publication Date:
31 December 2000 (online)
![](https://www.thieme-connect.de/media/synlett/199510/lookinside/thumbnails/10.1055-s-1995-5175-1.jpg)
A simple, mild and high-yielding procedure for the synthesis of β-phenethylamines is reported using facile reductive aminations of benzyl aldehyde and ketones with titanium(IV) isopropoxide and sodium borohydride.
Benzyl Ketone/Aldehyde - Reductive Amination - Titanium(IV) Isopropoxide - Sodium Borohydride - β-phenethylamines