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Synlett 1995; 1995(9): 955-956
DOI: 10.1055/s-1995-5132
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A Short and Efficient Synthesis of 4,5-Diarylpyrimidines

E. Domínguez* , E. Martínez de Marigorta, R. Olivera, R. SanMartín
  • *Kimika Organikoa Saila, Euskal Herriko Unibertsitatea, Posta Kutxatila 644, 48080 Bilbao, Spain
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Publication History

Publication Date:
31 December 2000 (online)

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4,5-Diarylpyrimidines 3 are efficiently prepared by submitting enaminones 2, readily obtained from deoxybenzoins 1, to Leuckart reaction conditions. This conversion implies an uncommon amine group exchange.

Pyrimidine - amine exchange - Leuckart - enaminone - deoxybenzoin