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Synlett 1995; 1995(9): 898-900
DOI: 10.1055/s-1995-5122
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Dispiroketals in Synthesis (Part 18)1: Regioselective and Enantioselective Protection of Symmetric Polyol Substrates Using an Enantiopure (2S,2’S)-Dimethyl-bis-dihydropyran

Paul J. Edwards, Steven V. Ley*
  • *Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
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Publication History

Publication Date:
31 December 2000 (online)

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The simultaneous enantioselective differentiation and regioselective protection of a range of acyclic symmetric polyols is investigated. Deprotection of a fully protected derivative leads to an enantiopure dissymmetric diol.

Regioselective and Enantioselective Protection - Polyol - Dispiroketal