Download PDF
Synlett 1995; 1995(7): 781-784
DOI: 10.1055/s-1995-5052
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Tuning the Reactivity of Glycosides: Efficient One-pot Oligosaccharide Synthesis1

Peter Grice, Steven V. Ley* , Jörg Pietruszka, Henning W. M. Priepke, Eric P. E. Walther
  • *University Chemical Laboratory, Lensfield Road, Cambridge CB2 1EW, UK
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Tuning the reactivity of glycosyl donors by selective introduction of different protecting and leaving groups enabled highly efficient oligosaccharide synthesis. Utilising both phenylseleno and ethylthio glycosides in combination with the cyclohexane-1,2-diacetal (CDA) protecting group provided four different levels of reactivity. One-pot sequential glycosidation of three components gave trisaccharides and tetrasaccharides.

Reactivity tuning - cyclohexane-1,2-diacetals (CDA) - one-pot synthesis - oligosaccharides

      >