PDF herunterladen
Synlett 1995; 1995(6): 653-654
DOI: 10.1055/s-1995-5038
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Stereoselective Construction of Functionalized Cyclopropane Ring through [2+1] Type Condensation of α,β-Enones and Chiral Aldehydes

Tadashi Sato* , Satoshi Nagatsuka
  • *Department of Applied Chemistry, Waseda University, Ookubo 3, Shinjuku-ku, Tokyo 169, Japan, Fax 03-3209-3692
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
31. Dezember 2000 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

Enolates obtained by the 1,4-addition of Me3SnLi to α,β-enones react with aldehydes or ketones to afford β-stannyl-β’-hydroxy ketones. Treatment of the products with methanesulfonyl chloride or other suitable reagents affords acyl cyclopropane derivatives. Complete chiral transfer from chiral aldehydes to cyclopropane ring was achieved.

Chiral cyclopropane - cyclopropanation - organotin - β-stannyl-β’-hydroxy ketones