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Synlett 1995; 1995(2): 157-158
DOI: 10.1055/s-1995-4904
DOI: 10.1055/s-1995-4904
letter
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Synthesis of 3-Pyridylpropenoic Acid Esters via Heck Coupling of Substituted 3-Pyridyl Triflates
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Publikationsverlauf
Publikationsdatum:
31. Dezember 2000 (online)
![](https://www.thieme-connect.de/media/synlett/199502/lookinside/thumbnails/10.1055-s-1995-4904-1.jpg)
From commercially available 3-hydroxypyridines, several 3-pyridinepropenoic ethyl esters were prepared in good yield via Heck coupling of ethyl acrylate and the pyridyl triflate. In general, LiCl accelerated the coupling, but was not required for all reactions.
Heck coupling - 3-Pyridyl triflates - 3-pyridylpropenoic acid esters - palladium