Synlett 1995; 1995(1): 29-31
DOI: 10.1055/s-1995-4878
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Asymmetric Addition Reaction to Non-Prochiral Carbonyl Compound: Asymmetric Catalytic Formaldehyde-Ene Reaction for Isocarbacyclin Synthesis

Koichi Mikami* , Akihiro Yoshida
  • *Department of Chemical Technology, Tokyo Institute of Technology, Meguro-ku, Tokyo 152, Japan
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Asymmetric catalysis of ene-type carbonyl addition to achiral/non-prochiral formaldehyde with the homotopic faces is described to provide a new route to the asymmetric synthesis of isocarbacyclin and 3-oxa analogues.