Synlett 1994; 1994(7): 487-489
DOI: 10.1055/s-1994-22898
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Cobalt-Catalyzed Entry Into the Ergot Alkaloids: Total Syntheses of (±)-Lysergene and (±)-LSD

Carlos Saá* , Dallas D. Crotts, Gishun Hsu, K. Peter C. Vollhardt
  • *Departamento de Química Orgánica, Universidad de Santiago de Compostela, Augas Férreas-Fingoi, 27002 Lugo, Spain
Further Information

Publication History

Publication Date:
18 September 2002 (online)

Cocyclization of 4-ethynyl-3-indoleacetonitriles with alkynes in the presence of CpCo(CO)2 gives rise to the ergoline derivatives 6-9, two of which were transformed into racemic lysergene and LSD, respectively.