PDF herunterladen
Synlett 1994; 1994(6): 445-446
DOI: 10.1055/s-1994-22884
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Asymmetric Induction in Radical Cyclization Leading to β-Lactams: Formal Synthesis of (+)-PS-5

Hiroyuki Ishibashi* , Chisato Kameoka, Tatsunori Sato, Masazumi Ikeda
  • *Kyoto Pharmaceutical University, Misasagi, Yamashina, Kyoto 607, Japan
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
18. September 2002 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

Tributyltin hydride-mediated radical cyclization of N-[2,2-bis(phenylthio)ethenyl]-α-bromoalkanamides bearing (S)-1-phenylethyl group on the nitrogen atom gave (4S)-4-bis(phenylthio)-methyl-2-azetidinones as major products. The method was applied to the synthesis of a chiral precursor of carbapenem antibiotic (+)-PS-5.