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Synthesis 1993; 1993(11): 1081-1083
DOI: 10.1055/s-1993-26003
short paper
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Preparation of 2-(ß-Oxo)-2-oxazolines and Thiazolines by Reaction of Enamines with 2-Chloroethyl Iso(thio)cyanates

Florence Castan* , Frederic Denonne, Dennis C. H. Bigg
  • *Centre de Recherche Pierre Fabre, 17 avenue Jean Moulin, F-81106 Castres, France
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Publikationsdatum:
29. April 2002 (online)

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Pyrrolidino enamines react with 2-chloroethyl iso(thio)cyanate to give, after hydrolysis, 2-(ß-oxo)-2-oxazolines and thiazolines in fair to good overall yield.