Download PDF
Synlett 1993; 1993(10): 764-766
DOI: 10.1055/s-1993-22601
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Reaction of Aziridines with Dianions Derived from ß-Ketoesters: Application to the Preparation of Substituted Pyrrolidines

Barry Lygo*
  • *Department of Chemistry and Applied Chemistry, University of Salford, Manchester, M5 4WT, England
Further Information

Publication History

Publication Date:
19 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

The nucleophilic ring opening of N-tosyl aziridines using the dianions derived from ß-ketoesters has been studied. Acid-mediated cyclisation of the resulting amino ß-ketoesters to a number of substituted pyrrolidines has also been examined.