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Synlett 1993; 1993(10): 758
DOI: 10.1055/s-1993-22598
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A Short High Yielding Route to Methyl 2-(Quinuclidin-2-yl)acetate

Barry S. Orlek*
  • *Smithkline Beecham Pharmaceuticals, Coldharbour Road, The Pinnacles, Harlow, Essex CM19 5AD, England
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Publication History

Publication Date:
19 March 2002 (online)

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The intramolecular Michael reaction of 3, which can be prepared in high yield from alcohol 4, provides the basis for a short efficient route to methyl 2-(quinuclidin-2-yl)acetate 1.