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Synlett 1993; 1993(6): 409-410
DOI: 10.1055/s-1993-22474
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Efficient Synthesis of 4-Methylene-L-glutamic Acid and its Analogues

Ouathek Ouerfelli* , Michiko Ishida, Haruhiko Shinozaki, Koji Nakanishi, Yasufumi Ohfune
  • *Suntory Institute for Bioorganic Research, Shimamoto-cho, Osaka 618, Japan
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Publication Date:
19 March 2002 (online)

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Three analogues of 4,4-disubstituted L-glutamate, 1~3, have been synthesized via a regioselective amino-carbonylation of an optically active propargylglycine equivalent prepared from L-aspartate.