Download PDF
Synlett 1993; 1993(5): 353-354
DOI: 10.1055/s-1993-22453
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A New Facile and Efficient Method for the Preparation of (Z)-α-Fluoro-β-(dialkylamino) acrylaldehydes from (Polyfuoro-1-propenyl)trimethylammonium Iodide

Hiroki Yamanaka* , Seiji Yamashita, Takashi Ishihara
  • *Department of Chemistry and Materials Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606, Japan
Further Information

Publication History

Publication Date:
19 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Treatment of (Z)-(2,3,3-trifluoro-1-propenyl)trimethylammonium iodide, available in three steps from 2,2,3,3-tetrafluoropropyl o-nitrobenzenesulfonate, with various secondary amines in aqueous dimethyl sulfoxide at 40-70°C gave rise to the corresponding Z isomers of α-fluoro-β-(dialkylamino)acrylaldehydes in good yields, together with a small amount of (Z)-α-fluoro-β-(dimethylamino)-acrylaldehyde.

      >