Synlett 1993; 1993(3): 235-236
DOI: 10.1055/s-1993-22416
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Intramolecular Ene-Based Approach to Furofuran Lignans: Total Synthesis of Neopaulownin

Koichi Mikami* , Hiroyuki Matsueda, Takeshi Nakai
  • *Department of Chemical Technology, Tokyo Institute of Technology, Meguro-ku, Tokyo 152, Japan
Further Information

Publication History

Publication Date:
19 March 2002 (online)

The lignan neopaulownin was synthesized in eight steps in 20% overall yield from piperonal by employing the type 5-(3,4) ene cyclization reaction of allylic (γ-aryl)propargyl ether as the key step.