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Synthesis 1992; 1992(7): 664-666
DOI: 10.1055/s-1992-26194
short paper
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A Convenient Synthesis of 1,2,5-Trisubstituted 4,5-Dihydroimidazoles and 1,3-Diazaspiro [4.4(5)]alk-2-enes from N-Alkylideneanilines

S. Shawkat Naim* , Satyavan Sharma
  • *Medicinal Chemistry Division, Central Drug Research Institute, Lucknow 226001, India
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Publication Date:
17 September 2002 (online)

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A convenient synthesis of 5-aryl-4,5-dihydro-2-methoxycarbonylamino-1-phenylimidazoles 5a-d and 2-methoxycarbonylamino-1-phenyl-1, 3-diazaspiro[4.4(5)]alk-2-enes 5e,f has been reported from N-alkylideneanilines 1a-f via cyclization of the corresponding 1,2-bis(methoxycarbonyl)-3-(2-anilinoalkyl)guanidines 4a-f.