Synthesis 1992; 1992(7): 641-642
DOI: 10.1055/s-1992-26185
short paper
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A Convenient One-Step Method of Converting Electron-Rich Aromatic Aldehydes into Nitriles

Hitomi Suzuki* , Chie Nakaya
  • *Department of Chemistry, Faculty of Science, Kyoto University, Sakyo-ku, Kyoto 606, Japan
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Publication History

Publication Date:
17 September 2002 (online)

Electron-rich aromatic aldehydes react with sodium azide in the presence of aluminum chloride in boiling tetrahydrofuran to give the corresponding nitriles in good yields, while electron-deficient or hindered aromatic aldehydes lead to (diazidomethyl)arenes in moderate yield under similar conditions.