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Synthesis 1992; 1992(7): 621-623
DOI: 10.1055/s-1992-26176
short paper
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An Efficient Synthesis of Enantiomerically Pure (R)-(2-Benzyloxyethyl)oxirane from (S)-Aspartic Acid

Jeffrey A. Frick* , John B. Klassen, Andreas Bathe, Jill M. Abramson, Henry Rapoport
  • *Department of Chemistry, University of California, Berkeley, California 94720, USA
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Publication Date:
17 September 2002 (online)

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A 3-step synthesis of the title compound from (S)-aspartic acid is described. The overall yield of this process is 65% and the enantiomeric purity (ep) of the product is greater than 99%