Synthesis 1991; 1991(11): 1043-1045
DOI: 10.1055/s-1991-26642
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A Simple Method for Preparation of Secondary Aromatic Amines

Ivan V. Mićović* , M. D. Ivanović, David M. Piatak, Vera Dj. Bojić
  • *Department of Chemistry, Faculty of Science, University of Belgrade, Studentski Trg 16, P. O. Box 550 YU-550 11001, Belgrade, Yugoslavia
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Publication History

Publication Date:
29 April 2002 (online)

A simple and efficient method for the preparation of secondary N-alkylarylamines via reductive amination of ketones with primary aromatic amines using activated zinc/acetic acid is described. It requires only equimolar amounts of the starting compounds and affords good yields of the corresponding amines (50-90%). It is not applicable to aldehydes nor aliphatic amines.