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Synthesis 1991; 1991(9): 750-752
DOI: 10.1055/s-1991-26566
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A New Synthesis of Nitriles from N-Alkoxyimidoyl Halides with Zinc

Takeshi Sakamoto* , Hirotoshi Mori, Mariko Takizawa, Yasuo Kikugawa
  • *Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-02, Japan
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Publication Date:
29 April 2002 (online)

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Both aliphatic and aromatic nitriles are obtained from the corresponding N-methoxy-, N-benzyloxy- or N- tert-butoxyimidoyl halides with zinc in a acetic acid/dimethylformamide mixture (1:1).