Synthesis 1991; 1991(8): 658-660
DOI: 10.1055/s-1991-26538
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Synthesis of 3-Amino-6-dimethylamino-4-oxopyrazolo[3,4-d] [1,3]oxazine Derivatives

Richard Neidlein* , Zhihua Sui
  • *Pharmazeutisch-Chemisches Institut der Universität Heidelberg, Im Neuenheimer Feld 364, D-6900 Heidelberg, Germany
Further Information

Publication History

Publication Date:
29 April 2002 (online)

3-Amino-1-aryl-6-dimethylamino-4-oxo-1,4-dihydropyrazolo[3,4-d][1,3] oxazines 4a-7a and 3-amino-2-aryl-6-dimethylamino-4-oxo-2,4-dihydropyrazolo [3,4-d][1,3]oxazines 4b-6b were synthesized from 4-chloro-5-cyano-2-dimethylamino-6-oxo-6H-1,3-oxazine 2 and arylhydrazines in good yields. The substituent effect of the arylhydrazines on the yields of products was clearly observed.