Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000084.xml
Synthesis 1991; 1991(1): 75-78
DOI: 10.1055/s-1991-26384
DOI: 10.1055/s-1991-26384
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
1-Alkylation of 4,5-Dicyanoimidazole by Ortho Esters
Further Information
Publication History
Publication Date:
17 September 2002 (online)
![](https://www.thieme-connect.de/media/synthesis/199101/lookinside/thumbnails/10.1055-s-1991-26384-1.jpg)
Reexamination of the reaction of ortho esters with diaminomaleonitrile (1) or 4,5-dicyanoimidazole (3a) revealed that 1-alkyl-4,5-dicyanoimidazoles 4a-f can be obtained in high yield in a one-pot procedure without any additional reagent. This simple procedure is economically competitive with other known methods. Several products previously reported for similar reactions have been shown to be the imidates of diaminomaleonitrile, 2b and 7.