Download PDF
Synlett 1991; 1991(6): 403-404
DOI: 10.1055/s-1991-20742
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Regio- and Stereoselective Opening of Phenyloxirane by Lithium Azide: A Direct Access to 2-Azido-1-phenylethanol

Alain Guy* , Thierry Dubuffet, Joël Doussot, Annie Godefroy-Falguieres
  • *Laboratoire de Chimie Organique (URA 1103) Conservatoire National des Arts et Métiers, 292 rue Saint-Martin, F-75141 Paris Cedex 03, France
Further Information

Publication History

Publication Date:
07 March 2002 (online)

 PDF Download  Permissions and Reprints All articles of this category

Regio-and stereoselective ring opening of styrene oxide (phenyloxirane) at the non-benzylic position was achieved by lithium azide/hexamethylphosphoric triamide. Optically pure (R)-2-azido-1-phenylethanol was obtained from the readily available (R)-phenyloxirane with complete retention of configuration.