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Synlett 1991; 1991(1): 37-38
DOI: 10.1055/s-1991-20620
DOI: 10.1055/s-1991-20620
letter
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A Mild and Efficient Sonochemical tert-Butoxycarbonylation of Amines from Their Salts
Further Information
Publication History
Publication Date:
07 March 2002 (online)
The introduction of the tert-butoxycarbonyl protecting group onto amines, as free bases or as salts, can be effected under mild conditions with ultrasonic irradiation. This method permits easy work-up and gives the protected compounds in high yield.