Synlett 1991; 1991(1): 37-38
DOI: 10.1055/s-1991-20620
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Mild and Efficient Sonochemical tert-Butoxycarbonylation of Amines from Their Salts

Jacques Einhorn* , Cathy Einhorn, Jean-Louis Luche
  • *Laboratoire d'Etudes Dynamiques et Structurales de la Sélectivité (LEDSS), Université Joseph Fourier, Grenoble I, BP 53X, F-38041 Genoble Cedex, France
Further Information

Publication History

Publication Date:
07 March 2002 (online)

The introduction of the tert-butoxycarbonyl protecting group onto amines, as free bases or as salts, can be effected under mild conditions with ultrasonic irradiation. This method permits easy work-up and gives the protected compounds in high yield.