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Synthesis 1990; 1990(11): 1079-1082
DOI: 10.1055/s-1990-27100
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A New Synthetic Route to α-Hydroxy Butyrolactones

Bruce B. Jarvis* , Kenneth M. Wells, Thomas Kaufmann
  • *Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA
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Publication History

Publication Date:
17 September 2002 (online)

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α-Oxocarboxylic acids react with olefins under acid conditions to give α-hydroxy butyrolactones (3-hydroxy-2-oxotetrahydrofurans) which can be readily dehydrated to give α,β-unsaturated butyrolactones 2-oxo-2,5-dihydrofurans.