Synthesis 1990; 1990(8): 659-660
DOI: 10.1055/s-1990-26972
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Studies on Pyrazines; Part 20.1 A Simple Synthesis of 5-Substituted 2-Amino-3-cyanopyrazines: Useful Intermediates for Pteridine Synthesis

Nobuhiro Sato* , Ryo Takeuchi
  • *Department of Chemistry, Yokohama City University, Yokohama 236, Japan
Further Information

Publication History

Publication Date:
17 September 2002 (online)

A new and convenient synthesis of 5-substituted 2-amino-3-cyanopyrazines 3 involving cyanation of the corresponding 2-amino-3-bromopyrazines 2 with sodium dicyanocuprate is reported.