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Synthesis 1990; 1990(2): 115-118
DOI: 10.1055/s-1990-26803
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α-Trifluormethyl-substituierte Aminosäuren mit Acetylenfunktionen in der Seitenkette

Klaus Burger* , Norbert Sewald
  • *Institut für Organische Chemie der Technischen Universität München, Lichtenbergstr. 4, D-8046 Garching, Federal Republic of Germany
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Publikationsdatum:
17. September 2002 (online)

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α-Trifluoromethyl Substituted Amino Acids with Alkyne Functions in the Side Chain Starting from trifluoro pyruvates and terminal alkynes a simple preparative procedure for synthesis of α-trifluoromethyl substituted acetylenic α-amino acids and α,ω-diamino dicarboxylic acids is described. The triple bond in the side chain can be functionalized manifoldly.