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Synlett 1990; 1990(7): 393-394
DOI: 10.1055/s-1990-21102
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Microbial Oxidation in Synthesis: Concise Preparation of (+)-Conduritol F from Benzene

Steven V. Ley* , Alison J. Redgrave
  • *Department of Chemistry, Imperial College of Science, Technology and Medicine, London SW7 2AY, England
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Publication Date:
08 March 2002 (online)

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A synthesis of the naturally occurring cyclohexenetetrol (+)-conduritol F [(+)-1], and its unnatural antipode (-)-1, has been developed in five steps from benzene using Pseudomonas putida oxidation to introduce the necessary cis-1,2-diol functionality.

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