PDF herunterladen
Synthesis 1988; 1988(12): 947-950
DOI: 10.1055/s-1988-27761
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of O-(α-Aminoacyl)glycolic and -lactic Amides from 2-Bromoacetamides or -propanamides with N-Protected Amino Acids

G. Cavicchioni* , F. D'Angeli, A. Casolari, P. Orlandini
  • *Department of Pharmaceutical Sciences, University of Ferrara, I-44100 Ferrara, Italy
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
20. August 2002 (online)

 als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

2-Bromocarboxamides carrying a primary, secondary or tertiary halide and a primary or secondary amide function react with N-protected amino acids in the presence of silver oxide to afford the desired depsipeptide analogs in high yields. Some racemization was observed in the synthesis of a lactoylamide derivative.