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Synthesis 1987; 1987(12): 1115-1116
DOI: 10.1055/s-1987-28189
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Optically Active N-Hydroxy-α-L-Amino Acid Methyl Esters: An Improved and Simplified Synthesis

Günter Grundke* , Wolfgang Keese, Manfred Rimpler
  • *Medizinische Hochschule Hannover, Abteilung Medizinische Chemie, Konstanty-Gutschow-Straße 8, D-3000 Hannover 61, West Germany
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Publication Date:
20 August 2002 (online)

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The preparation of optically active N-hydroxy-α-L-amino acid methyl esters from α-L-amino acid methyl esters is described. Readily available starting materials are used and the yields are good.