Download PDF
Synthesis 1987; 1987(8): 734-736
DOI: 10.1055/s-1987-28067
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

The Application of N-Substituted Trichloroacetamides as in situ Isocyanate Generating Reagents for the Synthesis of Acylureas and Sulfonylureas

Ivanka A. Atanassova* , Jan S. Petrov, Nikola M. Mollov
  • *Institute of Organic Chemistry with Centre of Phytochemistry, BAS Laboratory for Biologically Active Substances, 4002 Plovdiv, 75 I. Nikolova St., P.O. Box 27, Bulgaria
Further Information

Publication History

Publication Date:
12 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

In dimethylsulfoxide solution in the presence of excess of powdered sodium hydroxide, N-subsituted trichloroacetamides 1 are used as in situ isocyanate generating reagents which can react with carboxamides or sulfonamides 2 to afford acylureas or sulfonylureas 3.

      >