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Synthesis 1987; 1987(5): 510
DOI: 10.1055/s-1987-27987
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Rapid and Selective Formylation With Pentafluorophenyl Formate

Lajos Kisfaludy* , László Ötvös, Jr.
  • *Chemical Works of Gedeon Richter Ltd., H-1475 Budapest 10, P.O.B. 27, Hungary
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Publikationsdatum:
18. September 2002 (online)

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Pentafluorophenyl formate reacts smoothly with N-nucleophiles under mild conditions to give the N-formyl derivatives, whereas O- and S- nucleophiles remain unaffected even in the presence of a tertiary base.