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Synthesis 1987; 1987(2): 187-188
DOI: 10.1055/s-1987-27885
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Synthesis of Optically Active α-Fluoro-α-methyl-β-hydroxyesters of erythro or threo Configuration with Baker's Yeast

Tomoya Kitazume* , Tadashi Kobayashi
  • *Department of Bioengineering, Tokyo Institute of Technology, Ookayama, Meguro-ku, Tokyo 152 (Japan)
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Publication Date:
12 September 2002 (online)

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A number of optically pure α-fluoro-α-methyl-β-hydroxyesters of erythro or threo configuration were prepared by microbial transformation of α-fluoro-α-methyl-β-ketoesters with active fermenting baker's yeast.