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Synthesis 1986; 1986(12): 1031-1032
DOI: 10.1055/s-1986-31862
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The Reaction of Sulfinic Acid Salts with Hydroxylamine-O-sulfonic Acid. A Useful Synthesis of Primary Sulfonamides

S. L. Graham* , T. H. Scholz
  • *Department of Medicinal Chemistry, Merck Sharp & Dohme Research Laboratories, West Point, Pennsylvania 19486 U. S. A.
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Publication Date:
12 September 2002 (online)

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Hydroxylamine-O-sulfonic acid is shown to be a useful reagent for converting alkane- and arenesulfinic acid salts to the corresponding sulfonamides.