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Synthesis 1986; 1986(10): 811-817
DOI: 10.1055/s-1986-31788
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Selective Manipulation of Hydroxy Groups in (2S,3S)-Threitol

Seiichi Takano* , Ayako Kurotaki, Yoshinori Sekiguchi, Shigeki Satoh, Michiyasu Hirama, Kunio Ogasawara
  • *Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980, Japan
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Publication History

Publication Date:
20 August 2002 (online)

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Systematic transformation of diethyl (2R,3R)-tartrate into a number of protected or functionalized derivatives of threitol, which are important precursors for many natural products, is carried out employing reductive and oxidative cleavage reactions of benzylidene acetal bond.