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Synthesis 1986; 1986(6): 494-496
DOI: 10.1055/s-1986-31687
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Stereospecific Route to trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo[f]quinolines

Joseph G. Cannon* , Yu-an Chang, Victor E. Amoo, Kathleen A. Walker
  • *Division of Medicinal Chemistry and Natural Products, College of Pharmacy, The University of Iowa, Iowa City, Iowa 52242, U. S. A.
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Publication Date:
20 August 2002 (online)

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Access to the title compounds from unsaturated lactams 9 involves as the key step reduction of the carbon-carbon double bond with triethylsilane/trifluoroacetic acid reagent to give the trans-fused lactam product 10.