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Synthesis 1985; 1985(8): 738-742
DOI: 10.1055/s-1985-31329
DOI: 10.1055/s-1985-31329
paper
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On the Use of Five-Membered Heterocycles in Peptide Chemistry*
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Publication History
Publication Date:
17 September 2002 (online)
N-Acyl derivatives of 2-benzoxaolethiol, 2-benzothiazolethiol and 2-benzimidazolethiol are proposed for use both as efficient acylating agents for the synthesis of N-benzyloxycarbonyl and N-fluorenylmethyloxycarbonyl amino acid derivatives and as activated amides for the synthesis of peptides.