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CC BY-NC-ND 4.0 · Asian J Neurosurg
DOI: 10.1055/s-0046-1815953
Case Report

Spontaneous Disappearance of Intracranial Unruptured Saccular Aneurysms: Two Case Reports

Autor*innen

  • Shunsuke Shiraga

    1   Department of Neurosurgery, Kanazawa Medical University, Kahoku, Ishikawa, Japan

  • Keiichiro Torigoe

    1   Department of Neurosurgery, Kanazawa Medical University, Kahoku, Ishikawa, Japan

  • Takehiro Uno

    1   Department of Neurosurgery, Kanazawa Medical University, Kahoku, Ishikawa, Japan

  • Sho Takata

    1   Department of Neurosurgery, Kanazawa Medical University, Kahoku, Ishikawa, Japan

  • Toshihiro Ogiwara

    1   Department of Neurosurgery, Kanazawa Medical University, Kahoku, Ishikawa, Japan

  • Yasuhiko Hayashi

    1   Department of Neurosurgery, Kanazawa Medical University, Kahoku, Ishikawa, Japan
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Abstract

Spontaneous disappearance of small unruptured intracranial aneurysms is exceedingly rare, as most reported cases describe resolution in the context of rupture, giant aneurysms, or dissecting lesions. We report two cases of small saccular aneurysms that vanished during long-term magnetic resonance angiography follow-up. In Case 1, a 3.6 × 3.4-mm right internal carotid artery aneurysm demonstrated gradual reduction followed by complete disappearance, coinciding with proximal hemodynamic alteration. In Case 2, a 3.6 × 2.9 mm aneurysm of the right middle cerebral artery remained stable for 7 years before disappearing following asymptomatic M2 branch occlusion. These observations suggest that spontaneous thrombosis may occur even after prolonged morphologic stability, particularly when hemodynamic conditions shift toward reduced flow or altered shear stress. Recognition of this phenomenon is important for follow-up strategies, and additional imaging details are provided in the supplementary material.

Keywords

intracranial aneurysm - disappearance - spontaneous - thrombosis


Publikationsverlauf

Artikel online veröffentlicht:
03. Februar 2026

© 2026. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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