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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2025; 35(02): 350-355
DOI: 10.1055/s-0044-1793809
Case Report

Complete Androgen Insensitivity Syndrome: Role of Imaging for Diagnosis

Ravina Ravina
1   Department of Radiodiagnosis, Lady Hardinge Medical College, New Delhi, India
,
Nishat Amina
1   Department of Radiodiagnosis, Lady Hardinge Medical College, New Delhi, India
,
Anupran Ghosh
1   Department of Radiodiagnosis, Lady Hardinge Medical College, New Delhi, India
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Abstract

Androgen insensitivity syndrome (AIS) is a rare disorder of sexual differentiation, characterized by impaired responsiveness to androgens, resulting in the development of typically female external genitalia, despite having a male chromosomal pattern (XY). In this case report, we describe the radiological findings of two young siblings diagnosed with AIS who presented with primary amenorrhea. The diagnosis was confirmed on laparotomy and gonads were surgically removed in both the siblings.

Keywords

androgen insensitivity syndrome - androgens - ultrasound - magnetic resonance imaging - primary amenorrhea - Mullerian structures - gonads - secondary sexual characteristics


Publication History

Article published online:
19 November 2024

© 2024. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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