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CC BY-NC-ND 4.0 · Journal of Diabetes and Endocrine Practice 2024; 07(04): 185-194
DOI: 10.1055/s-0044-1791692
Original Article

Trend, Level, and Predictors of Glycemic Control among Iranians with Type 2 Diabetes: A 12-Year Retrospective Cohort Study

Authors

  • Amanuel Godana Arero

    1   Endocrinology and Metabolism Research Center, Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

  • Soghra Rabizadeh

    1   Endocrinology and Metabolism Research Center, Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

  • Mende Mensa Sorato

    1   Endocrinology and Metabolism Research Center, Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

  • Mohamad AlJasem

    1   Endocrinology and Metabolism Research Center, Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

  • Godana Arero

    2   Department of Public Health, Adama Hospital Medical College, Adama, Ethiopia

  • Alireza Esteghamati

    1   Endocrinology and Metabolism Research Center, Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

  • Nakhjavani Manouchehr

    1   Endocrinology and Metabolism Research Center, Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Funding None.
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Abstract

Objective We aimed to determine the trend, level, and predictors of glycemic control among adult type 2 diabetes on regular follow-up.

Material and Method A 12-year unmatched retrospective cohort study was conducted at Imam Khomeini Hospital, Tehran, Iran.

Statistical Analysis Descriptive statistics was computed for most variables, such as sociodemographic factors, medication-related factors, and disease-related factors. Multivariate logistic regression analysis was conducted to identify the functional independent predictors of good glycemic control among type 2 diabetes.

Results A total of 297 patients with regular follow-up were included in this study. Patients' mean body mass index was 28.51 ± 4.61 kg/m2. The mean glycated hemoglobin (HbA1c %) was 7.4 ± 1.25%. One hundred thirteen (30%) patients achieved the glycemic control target (i.e., HbA1c < 7.0%). The mean systolic blood pressure level was 132.88 ± 16.23 mm Hg. The mean diastolic blood pressure level was 76.58 ± 9.2 mm Hg. The mean level of low-density lipoprotein (LDL)-cholesterol was 79.23 ± 28.69 mg/dL. The highest trend of glycemic control was recorded in 2014 to 2015 (49.5%). Age less than 50 years, taking oral antidiabetic monotherapy, having blood pressure (BP) less than 140/90 mm Hg, and having LDL-cholesterol level < 70 mg/dL were independently associated with good glycemic control.

Conclusion Glycemic control levels among type 2 diabetes on regular follow-up were low. Young age was negatively associated with good glycemic control. Taking oral antidiabetic monotherapy, achieving BP, and meeting LDL-cholesterol targets were positively associated with good glycemic control. Therefore, addressing these factors can improve glycemic control and reduce associated complications.

Keywords

ABC control - type 2 diabetes - trends - predictors of good glycemic control - Iran

Declaration of Helsinki

The study was conducted following the ethical principles of the Declaration of Helsinki. Ethical clearance was obtained from Tehran University of Medical Sciences, and an official letter of approval was received from Imam Khomeini Hospital prior to the commencement of the research.


Authors' Contributions

All authors read and approved the manuscript. A.G.A. conceived the study, conducted data collection, framed the research design, and conducted data analysis. M.M.S. participated in data analysis and developed the manuscript. S.R., M.A., G.A., E.A., and M.N. reviewed the manuscript and polished the manuscript language.


Ethical Approval

Ethical clearance was obtained from the Tehran University of Medical Sciences, and Imam Khomeini Hospital prior to the commencement of the research.


Availability of Data Statement

Data concerning this manuscript is available upon reasonable request to the corresponding author.




Publication History

Article published online:
09 October 2024

© 2024. Gulf Association of Endocrinology and Diabetes (GAED). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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