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DOI: 10.1055/s-0044-1788925
Fetal Ganglioneuroblastoma: A Rare Entity with Antenatal Diagnosis and Postnatal Follow Up
Abstract
Fetal abdominal masses can be challenging to counsel due to uncertain diagnosis and outcomes. We report a case of a midline upper retroperitoneal mass found incidentally during a routine third trimester ultrasound. Despite not being a suprarenal mass, ultrasound and magnetic resonance imaging indicated neuroblastoma prenatally. With the generally favorable prognosis for prenatally diagnosed neuroblastomas, expectant counseling was given. Postnatal imaging and biopsy confirmed ganglioneuroblastoma, a rare subtype. A conservative approach was taken, and after initial growth, the mass spontaneously regressed 5 months after birth, nearly resolving by 8 months.
Publikationsverlauf
Artikel online veröffentlicht:
16. August 2024
© 2024. Society of Fetal Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
- 1 Cass DL. Fetal abdominal tumors and cysts. Transl Pediatr 2021; 10 (05) 1530-1541
- 2 Choi JH, Ro JY. Mediastinal neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: pathology review and diagnostic approach. Semin Diagn Pathol 2022; 39 (02) 120-130
- 3 Körber V, Stainczyk SA, Kurilov R. et al. Neuroblastoma arises in early fetal development and its evolutionary duration predicts outcome. Nat Genet 2023; 55 (04) 619-630
- 4 Van Arendonk KJ, Chung DH. Neuroblastoma: tumor biology and its implications for staging and treatment. Children (Basel) 2019; 6 (01) 12
- 5 Maki E, Oh K, Rogers S, Sohaey R. Imaging and differential diagnosis of suprarenal masses in the fetus. J Ultrasound Med 2014; 33 (05) 895-904
- 6 Andrei C, Vladareanu R, Zvanca M, Vladareanu S. Prenatal diagnosis of neuroblastoma. Donald Sch J Ultrasound Obstet Gynecol 2014; 8: 321-327
- 7 Werner H, Daltro P, Davaus T, Araujo Júnior E. Fetal neuroblastoma: ultrasonography and magnetic resonance imaging findings in the prenatal and postnatal IV-S stage. Obstet Gynecol Sci 2016; 59 (05) 407-410
- 8 Shin SI, Yoo JG, Park IY, Cheon JY. Prenatal diagnosis of fetal adrenal hemorrhage and endocrinologic evaluation. Obstet Gynecol Sci 2016; 59 (03) 238-240
- 9 Varlas V, Neagu O, Moga A. et al. Fetal pancreatic hamartoma associated with hepatoblastoma-an unusual tumor association. Diagnostics (Basel) 2022; 12 (03) 758
- 10 Brodeur GM. Spontaneous regression of neuroblastoma. Cell Tissue Res 2018; 372 (02) 277-286