Download PDF
CC BY-NC-ND 4.0 · International Journal of Epilepsy 2023; 09(01/02): 024-026
DOI: 10.1055/s-0044-1788708
Case Report

Wada Demonstrates Ipsilateral Language Function in Dyke-Davidoff-Masson Syndrome

Rutul Shah
1   Department of Neurology, Amrita Advanced Centre for Epilepsy, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India
2   Department of Neurology, K. D. Hospital, Ahmedabad, Gujarat, India
,
Siby Gopinath
1   Department of Neurology, Amrita Advanced Centre for Epilepsy, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India
,
Abhishek Gohel
1   Department of Neurology, Amrita Advanced Centre for Epilepsy, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India
2   Department of Neurology, K. D. Hospital, Ahmedabad, Gujarat, India
,
Sreelakshmi Narayanan
1   Department of Neurology, Amrita Advanced Centre for Epilepsy, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India
,
Ashok Pillai
3   Department of Neurosurgery, Amrita Advanced Centre for Epilepsy, Amrita Institute of Medical Sciences and Research Center, Kochi, Kerala, India
,
Ramiah Rajesh Kannan
4   Department of Neuroradiology, Amrita Advanced Centre for Epilepsy, Amrita Institute of Medical Sciences and Research Center, Kochi, Kerala, India
,
Talal Almashaikhi
5   Department of Clinical Physiology, Sultan Qaboos University Hospital, Seeb, Oman
› Author Affiliations
› Further Information
Also available at
   Permissions and Reprints

Abstract

Dyke-Davidoff-Masson syndrome (DDMS) is usually described secondary to prenatal or perinatal insult and is characterized by seizures, cerebral hemiatrophy, hemiparesis/facial asymmetry, and learning disability. We report an adolescent-onset case who presented with drug-refractory seizures and was considered for hemispherotomy on the dominant side. This is the first case report of DDMS where Wada helped in lateralizing the language to the ipsilateral dominant hemisphere despite the atrophy of the left inferior frontal gyrus. Thus, Wada is recommended in all patients without language regression who are considered for dominant hemispherotomy.

Keywords

Dyke-Davidoff-Masson syndrome - epilepsy - Wada test

Note

The current work has not previously been presented in a meeting or a conference.




Publication History

Article published online:
14 August 2024

© 2024. Indian Epilepsy Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Dyke CG. DLM and MCB. Cerebral hemiatrophy and homolateral hypertrophy of the skull and sinuses. Surg Gynecol Obstet 1933; 57: 588-600
    PubMedGoogle Scholar
  • 2 Atalar MH, Icagasioglu D, Tas F. Cerebral hemiatrophy (Dyke-Davidoff-Masson syndrome) in childhood: clinicoradiological analysis of 19 cases. Pediatr Int 2007; 49 (01) 70-75
    CrossrefPubMedGoogle Scholar
  • 3 Diestro JDB, Dorotan MKC, Camacho AC, Perez-Gosiengfiao KT, Cabral-Lim LI. Clinical spectrum of Dyke-Davidoff-Masson syndrome in the adult: an atypical presentation and review of literature. BMJ Case Rep 2018; 2018: 1-7
    PubMedGoogle Scholar
  • 4 Ghosh R, Mandal A, Roy D, Biswas S. Acquired Dyke-Davidoff-Masson syndrome presented with crossed non-aphasia. Int J Sci Res 2020; 8 (03) 5-6
    PubMedGoogle Scholar
  • 5 Hsin YL, Chuang MF, Shen TW, Harnod T. Temporo-spatial analyses define epileptogenic and functional zones in a case of Dyke-Davidoff-Masson syndrome. Seizure 2011; 20 (09) 713-716
    CrossrefPubMedGoogle Scholar
  • 6 Rasmussen T, Milner B. The role of early left-brain injury in determining lateralization of cerebral speech functions. Ann N Y Acad Sci 1977; 299: 355-369
    CrossrefPubMedGoogle Scholar
  • 7 Sieciechowicz D, Naduvil Valappil AM. . The role of language testing, Wada and fMRI, in patients with left sided hemispheric lesions considered for hemispherectomy. In: American Epilepsy Society Annual Meeting
    PubMed
  • 8 Loddenkemper T, Dinner DS, Kubu C. et al. Aphasia after hemispherectomy in an adult with early onset epilepsy and hemiplegia. J Neurol Neurosurg Psychiatry 2004; 75 (01) 149-151
    PubMedGoogle Scholar
  • 9 Shrestha B. Acquired cerebral hemiatrophy: Dyke-Davidoff-Masson Syndrome - a case report. Turk Neurosurg 2013; 23 (01) 117-121
    PubMedGoogle Scholar