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CC BY 4.0 · Indian J Med Paediatr Oncol
DOI: 10.1055/s-0044-1788312
Case Report with Review of Literature

An Exasperating and Unusual Presentation of Buschke-Lowenstein Tumor in an Adolescent Girl: Case Report with Review of Literature

Sony Nanda 
1   Department of Gynecologic Oncology, Acharya Harihara Institute of Cancer, Cuttack, Odisha, India
,
Janmejaya Mohapatra
1   Department of Gynecologic Oncology, Acharya Harihara Institute of Cancer, Cuttack, Odisha, India
,
Manoranjan Mahapatra
1   Department of Gynecologic Oncology, Acharya Harihara Institute of Cancer, Cuttack, Odisha, India
,
Jita Parija
1   Department of Gynecologic Oncology, Acharya Harihara Institute of Cancer, Cuttack, Odisha, India
,
Bhagyalaxmi Nayak
1   Department of Gynecologic Oncology, Acharya Harihara Institute of Cancer, Cuttack, Odisha, India
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Abstract

Giant condylomata acuminata of Buschke-Löwenstein (GCBL) is a benign condition with a high recurrence rate and a remote possibility of developing into cancer. It is characterized by excessive proliferation of verrucous lesions on the genitalia and/or perianal region, and is frequently linked to human papillomavirus (HPV) subtypes 6 and 11. With the exception of a few case series, case reports make up the majority of the literature. Despite the literature's support for surgical excision, the current evaluation reveals a lack of clarity regarding the disease's diagnosis and best course of action. Better assessment and management of these patients are necessary to prevent any progression/recurrence of disease.

Here, we present a case of a GCBL of the vulva in an 18-year-old girl, who was effectively treated with a simple vulvectomy and split skin graft reconstruction. The reported case is one of the rarest presentations of Buschke-Löwenstein tumor as it is not associated with any of the HPV subtypes and is seen in an 18-year-old girl, one of the youngest patients reported till date. This case report is followed by a brief review of the literature on GCBL, which will add to our understanding of this entity and the most effective therapy to treat the disease.

Keywords

giant condylomata acuminata - Buschke-Löwenstein tumor - human papillomavirus - adolescent - verrucous hyperplasia

Declaration of Patient Consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given her consent for her images and other clinical information to be reported in the journal. The patient understands that her name and initials will not be published and due efforts will be made to conceal her identity.




Publication History

Article published online:
18 July 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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