Full-Thickness Resection Device (FTRD) in Treating Upper GIT Lesions: A Retrospective Study

Introduction: The full-thickness resection device (FTRD) provides a novel treatment option for lesions not amenable to conventional endoscopic resection techniques. There are limited data on the efficacy and safety of FTRD for resection of upper gastrointestinal tract (GIT) lesions.

Methods: We conducted a retrospective study in a single quaternary care hospital. Patients who underwent endoscopic resection of an upper GIT lesion using the FTRD between January 2020 and February 2023 were analyzed in the study.

Results: Five patients were included. The common lesions were NET (n = 4, 80%), GIST (n = 1, 20%). 80% of the lesions were in duodenum and 20% were in stomach. The average size of the lesions was 15 mm (range: 10–25 mm). Deployment of the FTRD was technically successful in 100% of the patients, leading to complete resection in all the patients. Overall, the FTRD led to negative histological margins (R0 resection) in 100% of patients. 1 patient had mild postprocedure bleeding which was treated with Argon plasma coagulation (APC). Another patient had mal-deployment of the clip resulting in bleeding and perforation. It was managed endoscopically by OTSC clip. Follow-up endoscopy was performed in all patients on average of 45 days postprocedure. All patients did not have any residual or recurrent lesion on endoscopic examination and biopsy.

Conclusions: Our results suggest a high technical success rate and an acceptable histologically complete resection rate. Adverse events noted were mal-deployment of the clip with perforation and bleeding which was managed successfully.

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Publication History

Article published online:
22 April 2024