Endoscopy 2024; 56(S 02): S401
DOI: 10.1055/s-0044-1783696
Abstracts | ESGE Days 2024
ePoster

Comparative Evaluation of Endoscopic Anti-reflux Mucosectomy and Stretta Radiofrequency Ablation in the Management of Gastroesophageal Reflux Disease: Insights from a Retrospective Multi-Center Cohort Study

A. Y. Lee
1   Cha Medical Center Gangnam, Seoul, Republic of Korea
,
J. Y. Seo
2   분당제생병원 (Bundang Jesaeng Hospital), Seongnam-si, Republic of Korea
,
S. H. Kim
1   Cha Medical Center Gangnam, Seoul, Republic of Korea
,
J. Y. Cho
1   Cha Medical Center Gangnam, Seoul, Republic of Korea
› Author Affiliations
› Further Information
Also available at
 

Aims Treatment options for Gastroesophageal reflux disease (GERD) that is unresponsive to proton pump inhibitors (PPIs) are still not well-established. This study includes over 400 individuals who underwent anti-reflux mucosectomy (ARMS) or Stretta radiofrequency (SRF) for the treatment of intractable GERD and compares these two therapeutic methods for intractable GERD.

Methods This retrospective study, conducted from 2016 to 2023, evaluated the effectiveness of SRF and ARMS treatments for refractory GERD. The primary measure of success was the change in the GERD questionnaire (GERDQ) score. Secondary outcomes delved into various GERD-related indicators such as endoscopic Los Angeles (LA) classification, Hill’s type-based flap valve grade (FVG), EndoFLIP distensibility index (DI), rate of PPI discontinuation, resolution rate of Barrett’s esophagus, and incidence of adverse events.

Results The ARMS group included patients with more severe GERDQ scores, FVG, LA grade, and Barret’s esophagus. Although both groups showed similar GERDQ score improvements (P=0.884) and rates of PPI withdrawal (P=0.866), the ARMS group exhibited significantly more side effects but also superior results in GERDQ score (P=0.011), FVG (P<0.001), LA grade (P<0.001), EndoFLIP DI (P<0.001), and resolution of Barrret’s esophagus (P<0.001).

Conclusions The ARMS group showed greater GERDQ score improvement but had similar symptom relief and PPI discontinuation rates as the SRF group, despite more side effects. Objective measures, including EndoFLIP DI and endoscopic evaluations, were better in the ARMS group. [1] [2] [3] [4]



Publication History

Article published online:
15 April 2024

© 2024. European Society of Gastrointestinal Endoscopy. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • References

  • 1 Satodate H, Inoue H, Yoshida T. et al. Circumferential EMR of carcinoma arising in Barrett&apos;s esophagus: case report. Gastrointest Endosc 2003; 58 (02) 288-92
    CrossrefPubMedSearch in Google Scholar
  • 2 Richards WO, Houston HL, Torquati A, Khaitan L, Holzman MD, Sharp KW.. Paradigm shift in the management of gastroesophageal reflux disease. Ann Surg 2003; 237 (05) 638-47 discussion 648-9
    CrossrefPubMedSearch in Google Scholar
  • 3 Houston H, Khaitan L, Holzman M, Richards WO.. First year experience of patients undergoing the stretta procedure. Surgical Endoscopy And Other Interventional Techniques 2003; 2003 17 (03) 401-404
    CrossrefPubMedSearch in Google Scholar
  • 4 Spechler SJ, Lee E, Ahnen D. et al. Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial. Jama 2001; 285 (18) 2331-8
    CrossrefPubMedSearch in Google Scholar