An unexpected finding underlying colonic pseudolipomatosis

Abstract Text 56-year-old healthy asymptomatic woman, who underwent a screening colonoscopy. In the transverse colon: 15 mm whitish flat elevated lesion (Paris 0-IIa, NICE 1) (Fig 1). We perform an underwater endoscopic mucosal resection en bloc. Histopathological examination revealed a serrated sessile lesion (SSL) and multiple empty vacuoles in the lamina propria (Fig 2).

Colonic pseudolipomatosis (CP) is a rare benign condition usually asymptomatic that affects mostly the left colon [4] [5]. Its etiology is unclear but considered caused by mechanical or chemical endoscopic injury. CP regresses spontaneously within weeks or months [3]. To our knowledge, in the available literature there have been no previous reports describing CP with underlying SSL [3] and it should be noted this possibility and its different approach and surveillance [1] [2].

Publication History

Article published online:
15 April 2024

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